The Division of Biochemical Toxicology, National Center for Toxicological Research (NCTR) of the U.S. Food and Drug Administration (FDA).

Research efforts will include participation in multi-disciplinary efforts in a nationally recognized training program in support of the FDA’s mission to conduct fundamental and applied research designed to elucidate mechanisms of toxicity and support risk-assessment for chemicals of interest to the FDA. The selected participant will be trained under Dr. Annie Lumen and her team on the development and use of pharmacokinetic and mechanistic models on projects in support of NCTR’s objectives and the FDA mission.

Opportunities may include:

• Developing PBPK models for underrepresented life-stages to investigate and ensure the safety and efficacy of drugs repurposed for SARS-CoV-2 infection
• Characterizing life-stage specific variabilities to derive intra-population extrapolation strategies
• Simulating drug-drug interactions of medications used concomitantly for treating COVID-19 which may differ from typical clinical trial participants based on specific life-stages

The qualified candidate should have received a doctoral degree in one of the relevant fields, or be currently pursuing the degree with completion by May 31, 2021. Degree must have been received within five years of the appointment start date.

Preferred skills:

• Strong background in any modeling and simulation software (e.g., R, Berkeley Madonna, acslX, MCSim, Matlab, etc.)
• Knowledge of pharmacokinetics and toxicological principles
• Demonstrated written and oral communications skills

How to Apply

To be considered, please send a current CV/resume to the attention of annie.lumen@fda.hhs.gov